BPC-157 + TB-500, commonly referred to as the Wolverine stack, is a synthetic peptide blend formulated for advanced research into cellular repair, tissue regeneration, and inflammatory modulation.
The blend combines two well-studied peptides—BPC-157, derived from a protein found in gastric juice, and TB-500, a synthetic fragment of the naturally occurring Thymosin Beta-4 (TB-4) peptide.
BPC-157
BPC-157 (Body Protection Compound 157) is a 15-amino acid peptide shown in animal models to support angiogenesis, fibroblast activity, and tendon and ligament healing. It has also demonstrated protective effects in gastrointestinal and neurological injury models. Its strong stability in plasma, ease of solubility, and broad systemic activity make it a frequent subject in regenerative research.
TB-500
TB-500 is a synthetic peptide fragment designed to mimic the active region of Thymosin Beta-4, but with greater stability and shelf life, making it more practical for research storage and use. TB-500 promotes cell migration, blood vessel formation, and muscle fiber regeneration—key mechanisms in studies focused on soft tissue injury and cardiac repair.
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